References Leptocarpin and infusion


- Bosio, C. (2014). Mecanismo de acción por el cual Leptocarpina induce muerte celular programada en células (Magíster en Biotecnología). Universidad Andrés Bello, Viña del Mar, Chile. 

- Bosio, C., Tomasoni, G., Martínez, R., Olea, A. F., Carrasco, H., & Villena, J. (2015). Cytotoxic and apoptotic effects of leptocarpin, a plant-derived sesquiterpene lactone, on human cancer cell lines. Chemico-Biological Interactions, 242, 415-421. https://doi.org/10.1016/j.cbi.2015.11.006 

- Jiménez-González, A., Quispe, C., Bórquez, J., Sepúlveda, B., Riveros, F., Areche, C., Nagles, E., García-Beltrán, O., & Simirgiotis, M. J. (2018). UHPLC-ESI-ORBITRAP-MS analysis of the native Mapuche medicinal plant palo negro (Leptocarpha rivularis DC. – Asteraceae) and evaluation of its antioxidant and cholinesterase inhibitory properties. Journal of Enzyme Inhibition and Medicinal Chemistry, 33(1), 936-944. https://doi.org/10.1080/14756366.2018.1466880 

- Martínez, R., Kesternich, V., Carrasco, H., Álvarez-Contreras, C., Montenegro, C., Ugarte, R., ... & Cárcamos, J. (2006). SYNTHESIS AND CONFORMATIONAL ANALYSIS OF LEPTOCARPIN DERIVATIVES: INFLUENCE OF MODIFICATION OF THE OXIRANE RINGON LEPTOCARPIN'S CYTOTOXIC ACTIVITY. Journal of the Chilean Chemical Society, 51(4), 1010-1014. 

- Mena, C. 2008. Efecto apoptótico y quimiosensibilizador de Leptocarpina en distintos modelos celulares de leucemias. Tesis Lic. Química y Farmacia, Valdivia, Universidad Austral de Chile, Facultad de Ciencias.

- Olea, A. F., Villena, J., Moller, A., Martínez, R., & Carrasco, H. (2019). ENHANCEMENT OF CYTOTOXIC ACTIVITY BY ENCAPSULATION IN PLURONIC POLYMER MICELLES: LEPTOCARPHA RIVULARIS EXTRACTS AGAINST HUMAN CANCER CELL LINES. Journal of the Chilean Chemical Society, 64(2), 4437-4440. https://doi.org/10.4067/s0717-97072019000204437 

- Uquiche, E., Campos, C., & Marillán, C. (2019). Assessment of the bioactive capacity of extracts from Leptocarpha rivularis stalks using ethanol-modified supercritical CO2. The Journal of Supercritical Fluids, 147, 1-8. https://doi.org/10.1016/j.supflu.2019.02.005 

- Zheng, S.-, Wan, W.-, Miao, H.-, Tang, R., Wang, B., Huang, Q.-, Liu, W.-, Zheng, J.-, Chen, C.-, Zhong, H.-, Li, S.-, & Sun, C.-. (2017). Leptocarpin Suppresses Proliferation, Migration, and Invasion of Human Osteosarcoma by Targeting Type-1 Insulin-Like Growth Factor Receptor (IGF-1R). Medical Science Monitor, 23, 4132-4140. https://doi.org/10.12659/msm.903427